Somatic PRKAR1A mutation in sporadic atrial myxoma with cerebral parenchymal metastases: a case report
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چکیده
منابع مشابه
Left Atrial Myxoma in Children: A Case Report
Un gargon de 13 ans fut hospitalise dans le Service de Pediatrie du C.H.U. de Pahlavi de la Faculte de Medicine de Teheran, pour une insuffisance cardiaque. Les signes auscultatoires, radiologiques et electriques evoquaient une stenose mitrale. Le malade deceda <lans le tableau d'oedeme pulmonaire aigli, apres quelques episodes d'hemiparesies resolutives. A l'autopsie, il existait un myxcme...
متن کاملCerebral embolism complicating left atrial myxoma: a case report
Cardiac myxoma are the most common benign primary cardiac tumors that can lead to many complications as described in literature. Here we report the case of a boy aged 11 that was referred for etiological diagnosis of ischemic stroke. Transthoracic echocardiography reveals a myxoma in the left atrium. Patient was referred to surgery. The diagnosis was confirmed and the mass was completely resected.
متن کاملRare association of acromegaly with left atrial myxoma in Carney's complex due to novel PRKAR1A mutation
UNLABELLED Carney complex (CNC) is a rare autosomal dominant syndrome characterized by pigmented lesions of the skin and mucosae along with cardiac, endocrine, cutaneous, and neural myxomatous tumors. Mutations in the PRKAR1A gene have been identified in ∼70% of the CNC cases reported worldwide. A 30-year-old male was referred to the endocrinology clinic with suspected acromegaly. He had a hist...
متن کاملRecurrent somatic mutations of PRKAR1A in isolated cardiac myxoma
Background Cardiac myxomas are benign tumors that commonly arise within the left atria. Familial cardiac myxomas are a part of Carney Complex (CNC), an autosomal dominant multiple neoplasia syndrome caused by germline mutations in PRKAR1A. Seven percent of cardiac myxomas are associated with CNC. To date, the genetic basis of isolated cardiac myxomas (ICM), however, has not been fully elucidate...
متن کاملLeft Atrial Myxoma—A Case Report
Atrial myxomas are the most common primary cardiac tumors. More than 90% are solitary. A large myxoma occupying in the left atrium producing mitral stenosis and regurgitation was demonstrated by 2D echocardiographic images in this case. It remained asymptomatic for a long period with a survival up to the age of 75 years in an elderly female.
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ژورنال
عنوان ژورنال: Journal of Medical Case Reports
سال: 2019
ISSN: 1752-1947
DOI: 10.1186/s13256-019-2317-z